Olfactory and gustatory outcomes following endoscopic transsphenoidal hypophysectomy

Abstract Objective The aim of this study was to evaluate olfactory, gustatory, and quality-of-life outcomes in patients who underwent endonasal transsphenoidal hypophysectomy. Methods In prospective study, the were assessed subjectively using Malay version sQOD-NS (short questionnaire olfactory disorders a negative statement) objectively culturally adapted Sniffin’ Sticks smell test taste preoperatively 3 months postoperatively. consists odor identification, discrimination, threshold tests. different sweet, salt, sour, bitter concentrations. Results Twenty enrolled study. comprises 45% female 55% male. On average patients’ ages 49.5 years. we found significantly reduced identification score ( p = 0.049) post-surgery; however, there no statistically significant difference threshold, taste. quality life outcome based on 0.001) after surgery. There < 0.178) 0.425) pre-surgery post-surgery. tumor’s location, either sellar or suprasellar, did not influence postoperatively 0.056). Conclusion showed that endoscopic technique for pituitary surgery does pose permanent disability.